Angiotensin Vol.I

InhaltsangabePart 1: General Aspects.-General Physiology and Pathophysiology of the Renin-Angiotensin System. Phylogeny and Ontogeny of the Renin-Angiotensin System. Angiotensin as a Cytokine implicated in Accelerated Cellular Turnover. Regulation of Angiogenesis by Angiotensin II. Immunohistochemistry of Angiotensin. Renin-Angiotensin System: Plasma versus Tissues. Angiotensin-Endothelin Interactions.- Part 2: Genetics.- Genetics of the Human Renin-Angiotensin System. Knockout Models of the Renin-Angiotensin System. Transgenics of the RAS. Gene Therapy and the Renin-Angiotensin System.- Part 3: ANG Receptors.- AT1. AT1 Receptor Molecular Aspects. AT1 Receptor Interactions. AT1 Receptor Regulation. AT1 Receptor Signal Transduction. Sympathetic Interactions of AT1 Receptors. AT2.- Molecular Aspects of AT2 Receptor. AT2 Receptor of Angiotensin II and Cellular Differentiation. AT2 Renal Aspects. AT2 Function and Target Genes. AT1-7: Its Contribution to Arterial Pressure Control Mechanisms. Angiotensin AT4 Receptor.-