Beschreibung
InhaltsangabeCONTENTS 1. Sunlight, UV-Radiation, Vitamin D and Skin Cancer: How Much Sunlight Do We Need?. 1 Michael F. Holick Abstract. 1 Prehistorical and Historic Perspectives. 1 Photoproduction of Vitamin D3. 2 Factors Controlling Cutaneous Vitamin D Synthesis. 2 Sources and Metabolism of Vitamin D. 4 Role of Vitamin D in the Prevention of Chronic Diseases. 5 Vitamin D Deficiency Pandemic. 7 Sunlight, Vitamin D and the Skin Cancer Conundrum. 7 Conclusion. 10 2. Solar Ultrav iolet Irradiance and Cancer Incidence and Mortality. 16 William B. Grant Introduction. 16 Cancer. 16 Other Diseases for Which Solar UVB and Vitamin D Are Beneficial/Protective. 25 Summary and Conclusion. 25 3. Vitamin D Status and Cancer Incidence and Mortality. 31 Edward Giovannucci Introduction. 31 Ecologic Studies of Sun Exposure. 32 Case-Control and Cohort Studies of Sun Exposure. 32 Prospective Studies of Circulating 25(OH)vitamin D and Cancer Risk. 33 Studies of Vitamin D Intake. 35 Randomized Trial of Vitamin D Intake and Colorectal Cancer. 36 Solar Radiation, Vitamin D and Survival Rate of Colon Cancer. 36 Vitamin D and Cancer Rates in United States Black Men. 37 Synthesis of Evidence Regarding Sun Exposure, Vitamin D and Cancer Incidence and Mortality. 38 Implications for Future Research. 39 4. Sun Exposure and Cancer Surviva l in Norway: Changes in the Risk of Death with Season of Diagnosis and Latitude. 43 Alina Carmen Porojnicu, Arne Dahlback and Johan Moan Abstract. 43 Introduction.
